D. Wayne Lukas, 89, who has been a staple in horse racing since 1968 when he was training quarter horses at Los Alamitos, is leaving the game after contracting a potentially life-ending illness. In a note to owners and friends on Sunday, Lukas Enterprises announced: "We regret to inform you that D. Wayne Lukas will not be returning to racing. A severe MRSA blood infection has caused significant damage to his heart, digestive system, and worsened pre-existing chronic conditions. The doctors proposed an aggressive treatment plan, involving multiple surgeries and procedures over several months. Even with the best-case scenario, Wayne would require 24/7 assistance to manage daily activities." The note goes on to say that Lukas declined the aggressive treatment plan and would "return home to spend his remaining time with his wife, Laurie, his grandchildren and great-grandchildren." It also says that he will be under home hospice care. Read more:Commentary: Irascible D. Wayne Lukas brings energy to an otherwise dull Belmont Stakes Lukas is a member of both the U.S. Racing and Quarter Horse Halls of Fame. He has won the trainer Eclipse Award five times, and his horses have won 25 Eclipse Awards. In his career, Lukas has run 30,436 races, winning 4,953. His horses have earned over $300 million. His last significant win was in last year's Preakness Stakes, whichhe won with Seize the Grey. Get the best, most interesting and strangest stories of the day from the L.A. sports scene and beyond from our newsletter The Sports Report. This story originally appeared inLos Angeles Times.